Immune Infertility, Sperm Surface Antisperm Antibodies
Antisperm antibodies often are, but not always,
associated with testicular surgery or trauma.
Presence of AB should be suspected in men have a history of Vasovasostomy
and vasectomy reversal or other testicular surgery or injuries and when
sever Asthenospermia or spontaneous sperm agglutination is observed during
routine Semen Examination. Poor sperm penetration in PCT post coital
test with normal cervical mucus cross penetration test will help to find
out presence of antibodies in he sperm or cervical mucus.
factor covers 10 to 15 % of male infertility as a causative factor, these
include the patients in which all seminal parameters are normal but the
PCT Post Coital test are poor and there is defective sperm motility also
semen shows high level of sperm agglutination. In a couple with
Unexplained Infertility as well as when the man having history of
vasectomy reversal must be testing of AB Antisperm Antibodies.
Antibody AB test : Its very important to find out that weather actual
antibodies are present on the sperm itself (over tail, over head ) rather
than circulating in blood.
The presence of both IgG and IgA antisperm
antibodies are measured on the sperm surface. The results are given in
terms of the number of motile sperm affected by antisperm antibodies
surface antibodies may affect both movement of the sperm and the ability
of the sperm to bind to the oocyte results are clinically significant and
positive if more than 50% of sperm are affected by either class of
antibody. IgA antibodies are considered of greater clinical significance
Treatment : Homeopathic treatment
requires 4 to 6 month to solve the problem, In Allopathic science they
give steroids for treatment for sperm antibodies.